Endocrine Abstracts

There is little evidence of glycaemic control changes in Paediatric patients with diabetes during pandemics or natural disasters. We were interested in analysing and comparing the HbA1c values in children and young people with diabetes at West Hertfordshire NHS trust before the covid-19 pandemic in 2019-2020 and during lockdown in 2020-2021. Our hypothesis was that there would be a deterioration in HbA1c outcomes and a reduction in the number of tests done in 2020-2021. We ass...

Diabetes is a common presentation in children and young people. We describe a case of undiagnosed cystic fibrosis (CF), where diabetes was the presenting diagnosis. A 14 year old girl presented with a 2-month history of weight loss, abdominal pain, polyuria and polydipsia. Blood glucose was 31.4 mmol/l with ketones of 0.8 mmol/l, and a diagnosis of T1DM was made. Initial bloods showed HbA1c 150 mmol/mol, normal thyroid function, negative TTG, and negative TPO, GAD and IA2 anti...

Background: Diabetic ketoacidosis (DKA) can have significant morbidity and mortality in children and young people (CYP). Its management is very well standardised, based on National Guidance (National Institute of Clinical Excellence – NICE). In the UK, CYP DKA Guidelines have been reviewed in 2015 in order to reduce the risks of cerebral oedema. There have been concerns that the new recommended fluid management has the potential to increase the risk of acute kidney injury...

Introduction: The incidence of type 1 diabetes (T1DM) is increasing, affecting approximately 1 in 500 children and young people (CYP) under 19 years of age. The diagnosis of diabetes, as well as initial investigations and management is standardised, based on national guidance. Initial education and management have huge importance for long-term glycaemic control. We review the practice in our hospital, to establish our compliance and any deviations from the guidelines. We also ...

Sarcoidosis is a rare multisystem granulomatous disease that most commonly affects the lungs and skin, and can also affect eyes and lymph glands. We describe an unusual case of sarcoidosis presenting with hypercalcemia, causing diagnostic challenges. A 5year old boy was incidentally found to have asymptomatic hypercalcaemia during a routine clinic review for failure to thrive. Apart from a recent Influenza A infection, when he was found to have normal calcium levels and severe...